Candida infections both mucocutaneous and invasive - i.e. Candidemia
Cryptococcus and Coccidioides infections
Antifungal prophylaxis in immunocompromised
Consider QTc monitoring if concomitant drugs affecting the interval or elevated baseline measurement
Many via CYP450 - suggest review specific patient medications
Fluconazole increases levels of phenytoin, cyclosporine, tacrolimus, warfarin, oral hypoglycemics
Risk when combining with other QTc prolonging medications
Antimicrobial class: Triazole antifungal, decreases ergosterol synthesis
Pregnancy category: C
Average serum half life: 20.0
Biliary penetration: Therapeutic
CSF penetration: Therapeutic
Lung penetration: Therapeutic
Urine penetration: Therapeutic