MetroNIDAZOLE

C. diff Risk

Low

Oral Bioavailability

NA

Approximate Cost

<$1/day (Oral)

Dosing

> 2 kg

  • 0 – 7 days: 7.5 mg/kg/dose Q12h

  • > 7 days: 15 mg/kg/dose Q12h

1.2 - 2 kg

  • 0 – 7 days: 7.5 mg/kg/dose Q24H

  • > 7 days: 7.5 mg/kg/dose Q12H

< 1.2 kg

  • 0 – 4 weeks: 7.5 mg/kg/dose Q48H

General Information

First Line Indications

  • Treatment of C. difficile colitis
  • Treatment of infections or abscesses where anaerobes are major pathogens in combination with another agent for aerobic bacteria

Oral Liquids

Concentration: 50 mg/mL

Taste: Unpleasant taste

Not all strengths of oral liquids are listed nor be available on the CHEO Formulary

Tablet/Capsule Strengths

  • 250 mg

Tablets or capsules are preferred especially over an unpleasant tasting oral liquid.

Not all strengths of oral tablets/capsules are listed and they are not all available on the CHEO Formulary.