C. diff Risk


Oral Bioavailability


Approximate Cost

$2-3/day (Oral)

Spectrum Of Activity


Daily Dose: 2 - 4 mg/kg/day
Maximum Daily Dose: 200 mg
Dosing Frequency: PO/IV divided BID or q12h

IV therapy is only available through the Special Access Programme of Health Canada

There is no age contraindication if therapy does not exceed 21 days.

General Information

First Line Indications

Doxycycline is the optimal therapy for Lyme disease.

Oral Liquids

Concentration: 5 mg/mL (compounded)

Taste: Unpleasant taste

Not all strengths of oral liquids are listed nor be available on the CHEO Formulary

Tablet/Capsule Strengths

  • 100 mg

Tablets or capsules are preferred especially over an unpleasant tasting oral liquid.

Not all strengths of oral tablets/capsules are listed and they are not all available on the CHEO Formulary.