Amoxicillin - Pediatric Dosing

Daily Dose: 45 - 90 mg/kg/day
Maximum Daily Dose: 4000 mg/day
Dosing Frequency: PO divided TID

Note

  • Treatment of pneumonia, sinusitis or other indications should be with a three times a day (TID) dosing schedule.

  • Since the half-life of amoxicillin is one hour, a TID schedule will achieve higher levels for a more prolonged period of time.

  • Although TID dosing for AOM can also be used, BID dosing of amoxicillin has been approved for treatment of uncomplicated acute otitis media, albeit with higher doses (see BID dosing below).

Daily Dose: 75 - 90 mg/kg/day
Maximum Daily Dose: 4000 mg/day
Dosing Frequency: PO divided BID for AOM

Note

  • BID dosing of amoxicillin should only be used for treatment of uncomplicated AOM.