Sulfamethoxazole - Trimethoprim (TMP-SMX)

C. diff Risk


Oral Bioavailability


Approximate Cost


Spectrum Of Activity

General Information

First Line Indications

It is inappropriate to treat AOM or community-acquired pneumonia with TMP-SMX because of high levels of resistance of S. pneumoniae to TMP-SMX.

Oral Liquids

Concentration: 8 mg/mL TMP

Taste: Very good

Not all strengths of oral liquids are listed nor be available on the CHEO Formulary

Tablet/Capsule Strengths

  • 80 mg TMP(SS)

  • 160 mg TMP(DS)

Tablets or capsules are preferred especially over an unpleasant tasting oral liquid.

Not all strengths of oral tablets/capsules are listed and they are not all available on the CHEO Formulary.