AmpC - Organisms that produce AmpC beta-lactamase

Precautions

Contact Precautions
Contact Precautions

General Information

Pathogen information

Gram negative organisms, usually "SPICEM" (see additional information), that have a chromosomal beta-lactamase

Epidemiology

Most AmpC organisms are nosocomially encountered, are GI flora and are part of the Enterobacteriaceae family

Associated syndromes

Cause syndromes by the organism that possesses AmpC (see individual organism)

Additional Information

ESBLs vs. ampC: Most ESBLs are plasmid-encoded, whereas ampCs are usually inducible and chromosomal.

In the lab, ampCs test resistant to cefoxitin and cefotetan.

SPICEM stands for Serratia, Providencia, (Indole positive) Proteus vulgaris, Citrobacter, Enterobacter, and Morganella