Gram negative organisms, usually "SPICEM" (see additional information), that have a chromosomal beta-lactamase
Most AmpC organisms are nosocomially encountered, are GI flora and are part of the Enterobacteriaceae family
Cause syndromes by the organism that possesses AmpC (see individual organism)
ESBLs vs. ampC: Most ESBLs are plasmid-encoded, whereas ampCs are usually inducible and chromosomal.
In the lab, ampCs test resistant to cefoxitin and cefotetan.
SPICEM stands for Serratia, Providencia, (Indole positive) Proteus vulgaris, Citrobacter, Enterobacter, and Morganella