Surgical Prophylaxis

Note

Infusion of the first dose of antimicrobial should begin WITHIN 60 minutes of the surgical incision.

Exception: Vancomycin should be administered 1 to 2 hours prior to incision as it must be infused over minimum 1 hour.

No antimicrobials are routinely required post-operatively unless in exceptional circumstances or if being used for treatment purposes

Prolonged operations require re-administration of IV antimicrobials to maintain therapeutic levels at the site of wound closure if the operation lasts twice the half life of the antibiotic, if there is excessive blood loss or extended use of cardiopulmonary bypass.

Doses quoted are for the intravenous route and for patients with normal renal function. Do not exceed the maximum adult dose.