Cystic fibrosis, Pseudomonal infection
Not first-line therapy in children.
Antimicrobial class: Fluoroquinolone
Average serum half life: Pediatrics: 4-5 hours
Route of Elimination: 30% to 50% excreted as unchanged drug in urine via glomerular filtration and active tubular secretion; 20% to 40% excreted in feces primarily from biliary excretion; <1% excreted in bile as unchanged drug