Hospital Formulary Status Yes (parenteral inj)
In-Hospital Cost will be updated
PharmaCare Formulary Status Yes (parenteral inj)
SA None
PharmaCare Coverage 1g powder for soln/inj - $20.3580/vial 2g powder for soln/inj - $40.0680/vial
Outpatient Cost 1g powder for soln/inj - $20.36-22.39/vial 2g powder for soln/inj - $48.68-53.55/vial 6g powder for soln/inj - $146.13-160.74/vial
Broad gram negative coverage including Pseudomonas, generally used for nosocomial infections including post-neurosurgical meningitis, or other infections based on susceptibilities.
Notable lack of gram positive activity versus other cephalosporins.
Acute liver injury (IV)
Neutropenia (IV)
Thrombocytopenia (IV)
Allergic interstitial nephritis (IV)
Pulmonary infiltrate with eosinophilia (PIE) syndrome (IV)
CNS toxicity (IV)
Allergic reaction (IV)
Serum sickness (IV)
Rash (IV)
Note: EBV-related rash - not an allergy
Antimicrobial class: 3rd Generation Cephalosporin
Pregnancy category: B
Average serum half life: 2.0 hr
Urine penetration: Therapeutic
Lung penetration: Therapeutic
CSF penetration: Therapeutic
Biliary penetration: Moderate