Streptococcus pyogenes (GAS)


See 'Additional Information'
See 'Additional Information'

General Information

Pathogen information

Gram positive cocci in chains, beta-hemolytic


Reservoir is human skin and oropharynx/mucous membranes, colonizes 10% in pharynx, more commonly children

Person-to-person transmission, occasionally foodborne.

Associated syndromes

Exhaustive and fascinating list.

Most common manifestations are:

  • ¬†Tonsillopharyngitis ("Strep throat")

  • ¬†Skin infections (impetigo, erysipelas, cellulitis)

Other invasive infections:

  • Bacteremia

  • Endocarditis

  • Necrotizing fasciitis

  • Meningitis

  • Toxic shock syndrome

  • Pneumonia

  • Other sterile space infections.

Post-infectious immunologically mediated phenomena such as glomerulonephritis and rheumatic fever.

Scarlet fever.

Additional Information

Contact and droplet precautions for INVASIVE disease for the first 24hrs of antimicrobial therapy or after last debridement, otherwise no precautions.

Invasive disease is notifiable - call Public Health and Infectious Disease.

Post-exposure prophylaxis may be indicated.