Cefixime - Renal Dosing

In the setting of rapidly improving/worsening renal function, calculations of eGFR are inaccurate, and dosing should be based on estimated renal function instead.

If worsening renal function, actual GFR is likely lower than calculated.

If improving renal function, actual GFR is likely higher than calculated eGFR.

0 - 30 eGFR

200mg PO daily

30+ eGFR

400mg PO daily

200mg PO daily; give post-HD on dialysis days

200mg PO daily