Ampicillin

C. diff Risk

Low

Oral Bioavailability

NA

Approximate Cost

Dosing

1-2g IV q4-6h Meningitis or Endocarditis: 2g IV q4h

General Information

Common Usage

Pathogen directed therapy for CNS, intravascular, intraabdominal, urinary and other infections especially Enterococcus and Listeria

Adverse Effects

Allergy and rash as for all beta-lactams
EBV related rash (not allergy)
Rare: cytopenias, positive Coombs

Major Interactions

Increased risk of rash with allopurinol

Pharmacology

Antimicrobial class: aminopenicillin

Pregnancy category: B

Average serum half life: 1.0

Biliary penetration: Therapeutic

CSF penetration: Therapeutic

Lung penetration: Therapeutic

Urine penetration: Therapeutic