Skin and soft tissue infection (i.e. cellulitis), bone and joint infections, endocarditis
Surgical prophylaxis.
Susceptible Staphylococcal, Streptococcal and Gram negative infections.
Pregnancy: Compatible.
Breastfeeding: Compatible.
Allergy (immediate or delayed).
Can cause positive Coombs, cytopenias, and hepatic and renal laboratory abnormalities.
Probenecid prolongs half-life. Drug interaction has been used therapeutically to give once daily cefazolin
Antimicrobial class: 1st Generation Cephalosporin
Average serum half life: 2.0
Biliary penetration: Therapeutic
CSF penetration: Poor
Lung penetration: Therapeutic
Urine penetration: Therapeutic