2 g IV q8h
Skin and soft tissue infection (i.e. cellulitis), bone and joint infections, endocarditis
Susceptible Staphylococcal, Streptococcal and Gram negative infections.
Allergy (immediate or delayed).
Can cause positive Coombs, cytopenias, and hepatic and renal laboratory abnormalities.
Probenecid prolongs half-life. Drug interaction has been used therapeutically to give once daily cefazolin
Antimicrobial class: 1st Generation Cephalosporin
Pregnancy category: B
Average serum half life: 2.0
Biliary penetration: Therapeutic
CSF penetration: Poor
Lung penetration: Therapeutic
Urine penetration: Therapeutic