Cephalexin

C. diff Risk

Medium

Oral Bioavailability

Moderate

Approximate Cost

Spectrum Of Activity

Dosing

500mg PO QID

General Information

Common Usage

Uncomplicated skin and soft tissue infection, MSSA infections

Adverse Effects

Allergy/rash (immediate or delayed).

Can cause positive Coombs, cytopenias, eosinophilia, and hepatic and renal laboratory abnormalities

Major Interactions

Increases metformin levels

Pharmacology

Antimicrobial class: First generation cephalosporin - oral

Pregnancy category: B

Biliary penetration: Moderate

CSF penetration: Poor

Lung penetration: Moderate

Urine penetration: Therapeutic