Cephalexin

C. diff Risk

Medium

Oral Bioavailability

Moderate

Approximate Cost

Dosing

500mg PO QID

General Information

Common Usage

Uncomplicated skin and soft tissue infection, MSSA infections

Adverse Effects

Allergy/rash (immediate or delayed).

Can cause positive Coombs, cytopenias, eosinophilia, and hepatic and renal laboratory abnormalities

Major Interactions

Increases metformin levels

Pharmacology

Antimicrobial class: First generation cephalosporin - oral

Pregnancy category: B

Urine penetration: Therapeutic

Lung penetration: Moderate

CSF penetration: Poor

Biliary penetration: Moderate