Ertapenem - Renal Dosing

In the setting of rapidly improving/worsening renal function, calculations of eGFR are inaccurate, and dosing should be based on estimated renal function instead.

If worsening renal function, actual GFR is likely lower than calculated.

If improving renal function, actual GFR is likely higher than calculated eGFR.

0 - 25 eGFR

500mg IV q24h

25+ eGFR

1g IV q24h

500mg IV daily, dose after dialysis on HD days