Micafungin

C. diff Risk

Low

Oral Bioavailability

NA

Approximate Cost

Dosing

100mg IV daily

General Information

Common Usage

Therapy of suspected and confirmed invasive fungal infections

Adverse Effects

  • ¬†Increased liver enzymes

  • ¬†GI upset

Major Interactions

Increases levels of sirolimus and nifedipine (mild)

Additional Information

Requires ID or Antimicrobial Stewardship approval for onging use without an accepted indication

Pharmacology

Antimicrobial class: Echinocandin

Pregnancy category: C

Average serum half life: 15.0

Biliary penetration: Therapeutic

CSF penetration: Poor

Lung penetration: Therapeutic

Urine penetration: Poor