125 mg PO/NG/OG every 6 hr for 10-14 days Life-threatenting infections, ileus 500 mg PO/NG/OG every 6 hr for 10-14 days Intra-colonic dose 250 mg in 100mL of NS by rectal enema every 6 hr
Only indication is in the therapy of C. difficile infection, particularly recurrent or severe disease
Possibility of accumulation in severe renal dysfunction.
Consider checking a vancomycin level in dialysis patients.
No oral absorption.
May increase vancomycin resistant Enterococci colonization in the gut.
Antimicrobial class: Glycopeptide
Pregnancy category: B
Average serum half life: 0 hours
Biliary penetration: None
CSF penetration: None
Lung penetration: None
Urine penetration: None