Amikacin - Renal Dosing

CrCl > 60 ml/min

No dose adjustment necessary

CrCl 40- 60 ml/min

15 mg/kg/dose IV every 36 hr

CrCl 20-39 ml/min

15 mg/kg IV every 48 hr

CrCl < 20 ml/min

Call pharmacy

CrCl > 50 ml/min

No dose adjustment necessary

CrCl 10-50 ml/min

7.5mg/kg every 24 hr

CrCl < 10 ml/min

7.5 mg/kg every 48-72 hr

AVOID aminoglycosides in renal failure patients if possible.

5-7.5 mg/kg IV per hemodialysis session

10 mg/kg load then 7.5 mg/kg every 24 to 48 hr