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Pathogens
Antimicrobials
Low
NA
1-2 g IV every 4-6 hr
Meningitis or Endocarditis 2 g IV every 4 hr
Oral 500 mg PO QID
Pathogen directed therapy for CNS, intravascular, intraabdominal, urinary and other infections especially Enterococcus and Listeria
Laboratory
Clinical
Allergy and rash as for all beta-lactams
EBV related rash (not allergy)
Rare: cytopenias, +ve Coombs
Increased risk of rash with allopurinol
Antimicrobial class: Aminopenicillin
Pregnancy category: B
Average serum half life: 1 hour
Biliary penetration: Therapeutic
CSF penetration: Therapeutic
Lung penetration: Therapeutic
Urine penetration: Therapeutic