Cefuroxime

C. diff Risk

Medium

Oral Bioavailability

Moderate

Approximate Cost

Spectrum Of Activity

Dosing

500 mg PO every 12 hr

General Information

Common Usage

  •  Sinusitis

  •  Pharyngitis/tonsillitis

  •  Epiglottitis

  • Lyme disease

  • Impetigo

Adverse Effects

  •  Allergy (immediate & delayed)

  •  Positive Coombs

  •  Cytopenias

  •  GI upset

  •  Diarrhea

  •  Abnormal liver enzymes

Major Interactions

No significant interactions.

Pharmacology

Antimicrobial class: 2nd Generation Cephalosporin

Pregnancy category: B

Average serum half life: 2 hours

Biliary penetration: Therapeutic

CSF penetration: Poor

Lung penetration: Therapeutic

Urine penetration: Therapeutic