Prophylactic antibiotics not routinely indicated
Antibiotics not routinely indicated
Meropenem 1 g IV every 8 hr
Zosyn 3.375 g IV every 8 hr (4 hr infusion)
Levofloxacin 500 mg IV every 24 hr
Metronidazole 500 mg IV every 8 hr
For infected pancreatic necrosis, continue antibiotics for 14 days after source control is obtained.
Continuation of antibiotics beyond this time places the patient at risk for colonization or infection with resistant organisms and drug toxicity.
Antibiotics do not need to be continued until radiographic abnormalities have resolved.