Use Of Dexamethasone

Addition of dexamethasone is recommended in all adult patients with suspected pneumococcal meningitis (most community-aquired adult patients).

Dose: 0.15 mg/kg IV every 6 hr for 2-4 days

The first dose must be administered 10-20 minutes before or with the first dose of antibiotics (it should not be given to patients who have already started antibiotics).

Continue dexamethasone only if the CSF gram stain shows gram-positive diplococci or if the blood or CSF grows S. pneumoniae.