Clostridium difficile Infection (CDI) - Labs/Testing

Labs/Testing

Clostridium difficile GDH ToxinAB RfxPCR

Unpreserved stool specimen for molecular C. difficile toxin test.

Notes

If initial test is negative and clinical suspicion remains high, a second stool specimen test may be warranted after 7 days.

After initial positive result, repeat testing is NOT indicated to monitor response or carriage.

A positive test for C. difficile without symptoms does NOT require treatment.

Test all suspected cases of recurrent CDI. Empiric treatment should be avoided.