In the setting of rapidly improving or worsening renal function, calculations of CrCl are inaccurate. Dosing should be based on estimated renal function instead.
If improving renal function, actual CrCl is likely higher than calculated CrCl.
If worsening renal function, actual CrCl is likely lower than calculated CrCl.
Once Daily Dosing
Consult pharmacist for renal dose adjustment based on indication, renal function and peak/trough levels.
Traditional Dosing
Consult pharmacist for renal dose adjustment based on indication, renal function and peak/trough levels.