C. diff Risk


Oral Bioavailability


Approximate Cost


70 mg IV once then 50 mg IV daily

The manufacturer provides to dosing guideline. Not studied.
Severe Impairment (Child-Pugh Class C):

70 mg IV once then 35 mg IV daily
Moderate Impairment (Child-Pugh Class B):

No adjustment required
Mild Impairment (Child-Pugh Class A):

General Information

Common Usage

Therapy of suspected and confirmed invasive fungal infections

Adverse Effects

  • ¬†Increased liver enzymes

  • ¬†GI upset

Major Interactions

Decreases levels of Tacrolimus
Cyclosporine may increase levels of Caspofungin
Rifampin may decrease Caspofungin concentrations


Antimicrobial class: Echinocandin

Pregnancy category: C

Average serum half life: 10 hours

Biliary penetration: Therapeutic

CSF penetration: Poor

Lung penetration: Therapeutic

Urine penetration: Poor