Penicillin VK

C. diff Risk

Low

Oral Bioavailability

Moderate

Approximate Cost

Dosing

General Information

Common Usage

Streptococcal infections and therapy of documented susceptible infection not requiring parenteral therapy (i.e. upper respiratory tract).

Prophylaxis after rheumatic fever.

Drug Monitoring

  • ┬áMonitor for allergy.

  • ┬áPeriodic CBC, SCr

Adverse Effects

  • Allergy (anaphylaxis) and other rash

  • Cytopenias, Positive Coombs, Eosinophilia

  • Serum sickness

  • AIN

Major Interactions

No significant interactions

Pharmacology

Antimicrobial class: Penicillin

Pregnancy category: B

Average serum half life: 1 hour

Lung penetration: Therapeutic

Urine penetration: Therapeutic