Amoxicillin - Renal Dosing

In the setting of rapidly improving or worsening renal function, calculations of CrCl are inaccurate. Dosing should be based on estimated renal function instead.

If improving renal function, actual CrCl is likely higher than calculated CrCl.

If worsening renal function, actual CrCl is likely lower than calculated CrCl.

CrCl Greater Than 30 mL/min

250-500 mg TID

CrCl 10-30 mL/min

250-500 mg BID

CrCl Less Than 10 mL/min

250-500 mg q24h