1-2g IV q4-6h
2g IV q4h for meningitis or endocarditis
Pathogen directed therapy for CNS, intravascular, intraabdominal, urinary and other infections especially Enterococcus and Listeria
Allergy and rash as for all beta-lactams.
EBV related rash (not allergy).
Rare: cytopenias, +ve Coombs.
Increased risk of rash with allopurinol.
Antimicrobial class: Aminopenicillin
Pregnancy category: B
Average serum half life: 1 hour
Biliary penetration: Therapeutic
CSF penetration: Therapeutic with inflamed meninges
Lung penetration: Therapeutic
Urine penetration: Therapeutic