In the setting of rapidly improving or worsening renal function, calculations of CrCl are inaccurate. Dosing should be based on estimated renal function instead.
If improving renal function, actual CrCl is likely higher than calculated CrCl.
If worsening renal function, actual CrCl is likely lower than calculated CrCl.
Herpes zoster
1000 mg q8h
1000 mg q12h
1000 mg q24h
500mg q24h
Genital herpes (Initial)
1000 mg q12h
1000 mg q12h
1000 mg q24h
500 mg q24h
Genital herpes (Recurrent)
500 mg q12h
500 mg q12h
500 mg q24h
500 mg q24h
Herpes Labialis (Cold Sores)
2000 mg q12h x 2 doses
1000 mg q12h x 2 doses
500 mg q12h x 2 doses
500 mg single dose