Gentamicin Synergy - Adult Dosing

3mg/kg (S. viridans endocarditis)

1mg/kg

Interval
Note, the choice of the dosing interval is based on the patient's renal function. The patient's urinary output should be considered in addition to the serum creatinine concentration.

  • CrCl Greater Than 70 mL/min: Q8h
  • CrCl 40-69 mL/min: Q12h
  • CrCl 20-39 mL/min: Q24h
  • CrCl Less Than 20 mL/min: Give a dose and draw levels in 24 hours to determine dosing interval.