Typical cellulitis or erysipelas with systemic signs of infection:

  • Temperature over 38°C

  • Tachycardia

  • Tachypnea

  • Abnormal white blood cell count (over 12,000 or under 400 cells/µL)

Common Pathogens

Streptococcus pyogenes
(Group A β-hemolytic streptococci)

Methicillin-sensitive S. aureus

Empiric Regimen of Choice

Duration of Therapy

5-7 days, but in general treatment should be extended if the infection has not improved within this time period.