Indications for Prophylaxis


Intravenous Antibiotic Prophylaxis (IAP) is indicated at the onset of labour or rupture of membranes in the following settings:

1. Positive screening culture for GBS from vaginal/rectal swab

2. Positive history of birth of an infant with early-onset GBS disease

3. GBS bacteriuria during the current pregnancy

4. Unknown antepartum GBS status plus any of the following intrapartum risk factors in current pregnancy:

  • Intrapartum fever (greater than or equal to 100.4°F or 38°C)

  • Preterm labour (less than 37 weeks of gestation)

  • Prolonged rupture of membranes (greater than or equal to 18 hours)