Acyclovir - Pediatric Dosing

Creatinine Clearance >50mL/min/1.73m²

HSV neonate <3mo: 20mg/kg/dose IV Q8H

Creatinine Clearance 25-50mL/min/1.73m²

20mg/kg/dose IV Q12H

Creatinine Clearance 10-24mL/min/1.73m²

20mg/kg/dose IV Q24H

Creatinine Clearance ≤ 10mL/min/1.73m²

10mg/kg/dose IV Q24H

Dosing of acyclovir varies by immune status and indication. Please consult pediatric infectious diseases and/or pharmacy for dosing recommendations.