Amoxicillin

C. diff Risk

Low

Oral Bioavailability

Excellent

Approximate Cost

$

Dosing

Adult

500-1000mg PO TID

Renal

Dose reduction for CrCl < 30

General Information

Common Usage

Therapy of Streptococcal, Enterococcal infections as well as susceptible gram negative infections.

Commonly used for upper respiratory infections and urinary tract infection

Adverse Effects

Allergy/rash (immediate or delayed), cytopenias. Note EBV related rash

Major Interactions

Allopurinol - increased rash

Pharmacology

Antimicrobial class: Aminopenicillin

Pregnancy category: B

Average serum half life: 1 hour

Biliary penetration: Therapeutic

CSF penetration: Moderate

Lung penetration: Therapeutic

Urine penetration: Therapeutic