Amphotericin - Lipid Associated - Renal - Adult Dosing

Use total body weight for dosing. For patients with BMI >/= 35, adjusted body weight (AdjBW) is recommended

CrCl >50 mL/min

3-5 mg/kg/dose IV Q24h

CrCl <50 mL/min

Dose adjustment is unnecessary for pre-existing renal dysfunction however, decreased renal function caused by amphotericin may warrant dose adjustment (e.g. dose reduction or q48h dosing)