1-2 g IV q8h (max 6 gm/day)
Skin and soft tissue infection (i.e. cellulitis).
Susceptible Staphylococcal, Streptococcal and Gram negative infections.
Other GI effects
Probenecid - prolonged half-life. Drug interaction has been used therapeutically to give once daily cefazolin
Not recommended unless no other alternatives
Antimicrobial class: 1st Generation Cephalosporin
Pregnancy category: B
Average serum half life: 2 hours
Biliary penetration: Therapeutic
Lung penetration: Therapeutic
Urine penetration: Therapeutic
CSF penetration: Poor