Cephalexin

C. diff Risk

Medium

Oral Bioavailability

Moderate

Approximate Cost

$

Dosing

Adult

500 mg PO q6h

Renal

Dose reduction for CrCl < 30

General Information

Common Usage

Uncomplicated skin and soft tissue infection, MSSA infections

Drug Monitoring

Clinical

  • Hypersensitivity

  • Diarrhea

  • Other GI effects

Adverse Effects

  • GI effects

  • Hypersensitivity reactions

  • C. difficile

Major Interactions

Increases metformin levels

Pharmacology

Antimicrobial class: First generation cephalosporin - oral

Pregnancy category: B

Biliary penetration: Moderate

CSF penetration: Poor

Lung penetration: Moderate

Urine penetration: Therapeutic