Clindamycin - Pediatric Dosing

Creatinine Clearance >50mL/min/1.73m²

Intravenous
10mg/kg/dose IV Q8H
Maximum: 900mg/dose

Oral
10mg/kg/dose PO Q8H
Consider dividing doses over 450mg/dose

Creatinine Clearance 10-50mL/min/1.73m²

No change

Creatinine Clearance ≤10mL/min/1.73m²

No change

Creatinine Clearance >50mL/min/1.73m²

Intravenous
13mg/kg/dose IV Q8H
Maximum: 900mg/dose

Oral
13mg/kg/dose PO Q8H
Consider dividing doses over 450mg/dose

Consider dose reduction in hepatic insufficiency