General Spectrum of Activity

Gram positive: Methicillin Susceptible Staphylococcus aureus and susceptible Methicillin Resistant Staphylococcus aureus, Group A,B,C,G Streptococci (but increasing resistance), viridans streptococci.

Gram negatives: Essentially no aerobic Gram negative coverage.

Anaerobes: Increasing resistance in Bacteroides fragilis; covers many oral anaerobes.

Other: Pneumocyctis jiroveci, malaria, toxoplasma.

Does not cover: Almost all aerobic gram negatives, enterococci.