Macrobid 100mg PO BID
Contraindicated with CrCl < 60
Uncomplicated cystitis in females with normal renal function
Prolonged use may result in lung and skin toxicity. Caution advised.
Antacids decrease absorption
Think of this drug as a urinary antiseptic.
Not recommended in males due to inadequate tissue penetration, esp. with possible occult prostatitis.
Avoid in UTI with bloodstream infections or pyelonephritis.
Antimicrobial class: Nitrofuran
Pregnancy category: B [Contraindicated at term]
Average serum half life: 1 hour
Biliary penetration: None
CSF penetration: None
Lung penetration: None
Urine penetration: Therapeutic