Voriconazole - Pediatric Dosing

Loading Dose
6-9mg/kg/dose Q12H x2 doses, then

Maintenance Dose
4-9mg/kg/dose Q12H

No adjustment for renal dysfunction

The IV formulation should be avoided if possible if CrCl<50mL/min due to the accumulation of the IV vehicle.

Draw trough level ( ≤30 min before next dose) only after 5-7 days of treatment.

Loading Dose
400mg Q12H x2 doses, then

Maintenance Dose
200mg Q12H