Ampicillin-Sulbactam
Renal - Adult

Renal - Adult

Note

Higher doses may be used for infections due to MDR **Acinetobacter spp.**

Infectious Diseases Pharmacy: RRMC p99917; SMH p91059

Not On Dialysis

CrCl 15 to <30 ml/min

1.5-3 g IV Q12h

CrCl <15 ml/min (ESRD not on HD)

1.5-3 g IV Q24h

Dialysis

1.5-3 g IV Q12-24h (If Q24h, then give post-HD on dialysis days)

CVVHD

≤ 2 L/hr

3 g IV x 1, then 1.5-3 g IV Q6-8h

> 2 to 4 L/hr

3 g IV x 1, then 1.5-3 g IV Q6h

> 4 L/hr

Contact Infectious Diseases Pharmacy for assistance