Once Daily Oral Therapy for TB
15 to 25 mg/kg/dose-PO Q24H
Refer to adult dosing
Refer to adult dosing
Renal
Dosing adjustment not clearly established in pediatrics. Ethambutol is primarily renally eliminated and based upon available pharmacokinetic/pharmacodynamic data in adults, dose adjustment is warranted. The following recommendations are based upon the ADULT ATS/CDC/IDSA recommendations (2016) and only serve as a guideline
20-25 mg/kg/dose three times weekly. Do not administer daily dosing.
20 to 25 mg/kg/dose three times weekly. Given after dialysis on dialysis days.
Administer every 48 hours
Administer dose every 24H to 36H
Hepatic
No adjustments