Fidaxomicin

Restricted
Restricted

C. diff Risk

Low

Oral Bioavailability

None

Approximate Cost

$$$$

Dosing

Adult

200mg PO BID x 10 days for C. difficile

Pediatric

Refer to adult dosing.
No pediatric dosing recommendations at this time.

Restricted Use

Treatment of recurrent or refractory C difficile colitis in patients who have failed conventional therapy

General Information

Adverse Effects

  •  Hypersensitivity: facial, tongue, or throat swelling

  •  GI disturbance

  •  Cytopenias

Additional Information

  •  Non-formulary

  •  Consult Infectious Disease

Pharmacology

Antimicrobial class: Specialized anti-C. diffile macrocyclic agent

Pregnancy category: B

Average serum half life: 0 hours

Biliary penetration: None

CSF penetration: None

Lung penetration: None

Urine penetration: None