Neisseria meningitidis

Precautions

Droplet Precautions
Droplet Precautions

General Information

First Line Treatment

  • Ceftriaxone

See CNS Infections in the Syndrome section.

Alternate Treatment

  • Ampicillin

See CNS Infections in the Syndrome section.

Prophylaxis (with Hospital Epidemiology input)

  • Ciprofloxacin

  • Rifampin

Pathogen information

Encapsulated Gram negative diplococci

Epidemiology

Normal flora - humans are the reservoir.

Quadrivalent vaccine prevents disease by serogroups A/C/W-135/Y.

Occurs in outbreaks particularly in crowded setting.

Associated syndromes

Colonizer and cause of invasive disease:

  • Meningitis

  • Meningococcemia

  • Rarely pneumonia

  • Septic arthritis

  • Pericarditis

  • Conjunctivitis

  • Others

Generally of little significance when cultured from nonsterile sites i.e. genital, pharynx.

Additional Information

Invasive meningococcal disease is notifiable - call Public Health ASAP

Droplet precautions until 24hrs of appropriate antimicrobial therapy

Prophylaxis may be required for close contacts and healthcare workers; contact Clinical Epidemiology