Stenotrophomonas maltophilia

Precautions

Standard Precautions

General Information

First Line Treatment

TMP/SMX

Typically causes colonization (e.g. airways) and no treatment needed unless isolated from a sterile site

Alternate Treatment

  • Levofloxacin

  • Meropenem

  • Tigecycline

  • Doxycycline

Pathogen information

Aerobic non-fermenting Gram negative rod

Epidemiology

May be acquired from diverse environmental sources (i.e. tap water).

Bronchiectatics may be colonized (i.e. CF patients).

Must distinguish colonization from clinically significant infection.

Associated syndromes

Most common reason for isolation is colonization of the respiratory tract.

Most common true infections - blood stream infection (usually from vascular catheter) and pneumonia. Other manifestations rare (endocarditis, sinusitis, cellulitis, etc)

Additional Information

True pneumonia more likely in ICU and oncology patients, those with advanced age and after/during treatment with broad spectrum antimicrobial use.