Staphylococcus aureus

Precautions

See 'Additional Information'
See 'Additional Information'

General Information

First Line Treatment

Methicillin-S (MSSA)

  • Oxacillin

  • Cefazolin

  • Dicloxacillin

Methicillin-R (MRSA)

  • Vancomycin

Vancomycin intermediate or resistant (VISA, VRSA)

  • Consult ID

Alternate Treatment

Methicillin-S (MSSA)

  • Clindamycin

  • TMP/SMX

  • Doxycycline

  • Ceftriaxone

Methicillin-R (MRSA)

  • Linezolid

  • Daptomycin

  • TMP/SMX

  • Doxycycline

  • Clindamycin

Vancomycin intermediate or resistant (VISA, VRSA)

  • Consult ID

Pathogen information

Gram positive cocci in clusters, Coagulase positive

Epidemiology

Staph aureus is a ubiquitous organism that colonizes the skin/nares and can cause invasive disease.

MRSA risk factors include health care exposure (hospitalization, hemodialysis), antimicrobial use, incarceration, IDU, shared equipment and others

Associated syndromes

Highly virulent organism

Infection manifests as:

  • Pyogenic skin and soft tissue infection

  • MSK infection

  • Endocarditis

  • Abscess

  • ┬áPneumonia

  • Infection of prosthetic devices

  • Others

Additional Information

MRSA: Standard Precautions*

*Contact Precautions for:

  • Major skin, wounds, burns.

  • S. aureus enterocolitis in children, infants, and incontinent

  • S. aureus Scalded Skin Syndrome (Ritter's)