Cefepime 2g IV q8h
Pip/Tazo 3.375g IV q8h.
Infused over 4 hours
If Pseudomonas is NOT recovered and organisms are not susceptible to agents with a narrower spectrum of activity, lower doses as follows.
Cefepime 1g IV q8h
Aztreonam 2 gm q8 IV
Catheters are less commonly the source of the infection; however, most advocate catheter removal if the catheter is the source
Gram-negative endocarditis is extremely rare. Routine echocardiography is not advised
unless there is high clinical suspicion of endocarditis.