A progressively destructive infection of the subcutaneous tissue tracking along the superficial fascia with involvement of all tissue between the skin and underlying muscle; skin may be spared

Fournier gangrene: a variant of necrotizing soft tissue infection that involves the scrotum and penis or vulva. Infections are commonly polymicrobial involving both aerobic and anaerobic flora.

Cases of fasciitis caused by community-acquired MRSA have been reported

Case-cohort studies and case reports have suggested some benefit to treatment with intravenous immunoglobulin (IVIG) in specific circumstances (e.g., streptococcal toxic shock). However, due to the lack of randomized controlled trials, IVIG should probably be reserved for select patients. Infectious Diseases consult is advised.