Endocarditis Prophylaxis

Candidates for Prophylaxis

Only those patients with conditions associated with the highest risk for adverse outcomes from IE should receive prophylaxis.

High-Risk Conditions

Prosthetic cardiac valves (both bioprosthetic and mechanical)

Previous infective endocarditis

Congenital heart disease (CHD) only for the following specific conditions:

  • Unrepaired cyanotic CHD, including palliative shunts and conduits.

  • Completely repaired congenital heart defect with prosthetic material or a prosthetic device placed either during surgery or by catheter intervention, during the first 6 months after the procedure

  • CHD repair with residual defects at the site or adjacent to the site of a prosthetic patch or prosthetic device

Development of cardiac valvulopathy after cardiac transplantation